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Planta Medica | 全新天然药物研究内容精选 2022-10-26

Brand New Natural Product Research Content

蜂胶或蜂胶是蜜蜂的树脂混合物,用于传统医学。如果您认为您对这个仍然神秘的药物了如指掌,请阅读这篇优秀的综述。对近200项研究进行了分析,14项进行了详细综述,以了解其对糖尿病的影响。Aparecido da Cunha 等人清楚地记录了在糖尿病动物中的显著降糖作用。令人兴奋的是,氧化应激的减少是一种有趣的作用方式。本篇论文是对这一现代研究课题有长期期望更新的精彩综述。

已知化合物,但在眼科中具有新活性!Liberato 等人强调了绿原酸衍生物在保护视网膜疾病方面的潜力,例如眼压升高(青光眼)和眼睛的退行性神经病变。这些出色的研究确定了可能的作用机制,并评估了眼压升高诱导的缺血再灌注应用模型中的凋亡、氧化应激、炎症信号通路。

欢迎阅读本期两篇精选论文。

Review

A Systematic Review of the Potential Effects of Propolis Extracts on Experimentally-induced Diabetes

Aparecido da Cunha et al. 

Oxidative stress (OS) is involved in the development of diabetes mellitus (DM) and its complications. Thus, OS reduction may be an important strategy for DM therapy. Propolis is bee resins with high antioxidant activity and is used in the treatment of different diseases, including DM. Therefore, in this systematic review, we evaluated the impact of propolis administration in diabetic animals. 

Original Papers

Neuroprotective Properties of Chlorogenic Acid and 4,5-Caffeoylquinic Acid from Brazilian arnica (Lychnophora ericoides) after Acute Retinal Ischemia

Liberato et al.

Lychnophora is a genus of South American flowering plants in the daisy family, popularly known as “Brazilian arnica”. It is used in traditional medicine as an anti-inflammatory and analgesic agent, whose active components are derived from chlorogenic acid (CGA) and C-flavonoids. Since the drugs currently used are ineffective to treat glaucoma, agents with antioxidant and anti-inflammatory properties may represent new alternatives in preventing cellular lesions in retinal ischemia. 

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