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Thrombosis and Haemostasis | Author Interview 2022-06-18
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Thrombosis and Haemostasis

Author Interview

Letter to the Editor

Thrombosis and Thrombocytopenia Syndrome Causing Isolated Symptomatic Carotid Occlusion after Covid-19 Vaccine

Jorge Rodríguez-PardoFrancisco Gilo-ArrojoGerardo Ruiz-AresJuan Carlos Sánchez-MansoEsther Valiente-GordilloElena de CelisBlanca FuentesÁlvaro Ximénez-CarrilloMaría Alonso de LeciñanaRicardo RigualJosé Vivancos-MoraExuperio Díez-Tejedor

Thromb Haemost 2022; 122(02): 300-303
DOI: 10.1055/a-1674-0341

T&H


Why did you (and your colleagues) write this paper? What was its main purpose?

JORGE RODRIGUEZ-PARDO

Our paper describes a well-documented case of stroke caused by a carotid floating thrombus related to COVID-19 vaccination. We wanted to share our experience with the scientific community to contribute to a better understanding of this disease. This case could inspire future research on the topic. 

T&H


What are the main conclusions? 

JORGE RODRIGUEZ-PARDO

We conclude that vaccine-induced immune thrombosis may cause isolated large vessel occlusion stroke in absence of severely altered coagulation parameters or venous thrombosis. 

T&H


What are the paper's implications? - to the public? -to medical professionals?

JORGE RODRIGUEZ-PARDO

We acknowledge that stroke is a rare complication of COVID-19 vaccines and should not discourage their use. 

It encourages stroke physicians to consider vaccine-induced immune thrombocytopenia as a potential cause of unusual carotid and cerebral artery thrombosis in recently vaccinated patients. 

T&H


Are the findings clinically significant? Should the findings change practice? 

JORGE RODRIGUEZ-PARDO

As a single case report it lacks significant evidence for a change of clinical practice although it contributes to cumulative knowledge and raises questions for future studies.