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HMR Issue 5/2022: 主编精选论文免费阅读 2022-06-02
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内分泌学期刊Hormone and Metabolic Research第5期现已上线,欢迎免费阅读本期三篇主编精选论文。

Issue 05 · Volume 54 · May 2022

Original Article: Endocrine Care

Exploration of Core Genes in ACTH-Independent Macronodular Adrenal Hyperplasia

Junwu Li , Yunhui Wang, Qinke Li, Ronggui Zhang

重庆医科大学附属第二医院

This study explores the core genes involved in the pathogenesis of ACTH-independent macronodular adrenal hyperplasia (AIMAH), so as to provide robust biomarkers for the clinical diagnosis and treatment of this disease. Gene Expression Omnibus (GEO) database was used to obtain GSE25031 microarray dataset. R package “limma” was applied to identify differentially expressed genes (DEGs) between AIMAH and normal samples...

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Original Article: Endocrine Care

Adrenal Surgery in the Era of Multidisciplinary Endocrine Tumor Boards

Chiapponi C et al.

Work up of adrenal masses includes assessment of endocrine activity and malignancy risk. There is no indication for surgical removal of nonfunctional adrenal adenomas, according to the guidelines. In the present study, we aimed at evaluating the impact of a university endocrine tumor board on the quality of the indications for adrenal surgery at our institution. One hundred consecutive patients receiving primary adrenal surgery at the University Hospital of Cologne, Germany were included...

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Review

Cardiac Remodeling in Hypertension: Clinical Impact on Brain, Heart, and Kidney Function

Mavrogeni S et al.

Hypertension is the most common causative factor of cardiac remodeling, which, in turn, has been associated with changes in brain and kidney function. Currently, the role of blood biomarkers as indices of cardiac remodeling remains unclear. In contrast, cardiac imaging, including echocardiography and cardiovascular magnetic resonance (CMR), has been a valuable noninvasive tool to assess cardiac remodeling...

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