The Efficacy of Saffron in the Treatment of Mild to Moderate Depression: A Meta-analysis

Tóth B et al.

| Fig. 2 Effects of saffron on the severity of mild to moderate depression compared to placebo in a random effects model (n = 5).

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Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder

El-Elimat T et al.

| Fig. 3  Comparison of exploratory activity in terms of (A) the time spent and (B) number of entries made to the central quadrant in the OFT among the control, silymarin, SPS, and SPS + silymarin groups with n = 14, 13, 16, and 17 in each group, respectively. SPS-induced rats spent significantly less time (F(3, 51) = 3.455, p = 0.020) and made a fewer number of visits to the central quadrant (F(3, 49) = 3.42, p = 0.024). Silymarin administration normalized exploratory activity, although it did not reach significance. Reported values are mean ± SEM. * denotes statistical significance from control.

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Natural Product Triterpenoids and Their Semi-Synthetic Derivatives with Potential Anticancer Activity

Ren Y, Kinghorn AD.

Stellera chamaejasme and Its Main Compound Luteolin 7-O-Glucoside Alleviates Skin Lesions in Oxazolone- and 2,4-Dinitrochlorobenzene-Stimulated Murine Models of Atopic Dermatitis

Jo BG et al.

| Fig. 5 Effects of SCAE and luteolin 7-O-glucoside on skin barrier function in DNCB-induced atopic hairless mice. CON: control group, DNCB: 0.1% DNCB-treated group, DNCB-SCAE: 0.1% DNCB and 0.5% SCAE co-treated group, DNCB‑lut-7-glc: 0.1% DNCB and 0.5% luteolin 7-O-glucoside cotreated group, DNCB-Elidel: 0.1% DNCB and 1% Elidel co-treated group. An Aquaflux AF103 (Biox system) was used to measure transepidermal water loss (TEWL) values and a SKIN‑O‑MAT (Cosmomed) was used to evaluate the skin hydration. TEWL and skin hydration were measured weekly under standard conditions (25 ± 5°C, 55 ± 5% RH). A The amount of TEWL in the DNCB-SCAE group. B Estimation of skin hydration in the DNCBSCAE group. C Amount of TEWL in the DNCB‑lut-7-glc or 1% Elidel group. D Estimation of skin hydration in the DNCB‑lut-7-glc or 1% Elidel group. Results are expressed as means ± SEMs (n = 7). The means ± SEMs of two independent experiments are shown; #p < 0.05 vs. treatment naïve controls,

*p < 0.05 vs. DNCB-treated controls.

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Antiplasmodial Lycorane Alkaloid Principles of the Plant Family Amaryllidaceae

Nair JJ, van Staden J.

| Fig. 2 Semisynthetically derived lycorane alkaloids that have been screened for antiplasmodial effects.

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Planta Medica为天然药物领域的国际领先期刊之一 - 包括海洋生物、真菌以及微生物和药用植物。Planta Medica 接受来自全球研究人员的原创研究论文、述评、短评和观点。本刊每年出版 18 期。涵盖药用植物和天然药物研究的以下领域：

• 生物学和药理学活性

• 天然药物化学与分析研究

• 药代动力学研究

• 天然药物的配方和传输系统

本刊特别鼓励具有化学特点的摘要投稿。

药用植物和天然药物研究协会 (GA) 会刊：www.ga-online.org