Endoscopy最新一期现已上线,欢迎免费阅读本期三篇主编精选论文。
在巴氏食道症 (BE) 患者中,由病理学专家证实的低度不典型增生是恶性变性的有力预测指标。在BE专家中心,从社区医院转诊的248例此类患者中,近四分之一被重新分期为患有高度不典型增生或癌症。Nieuwenhuis等人还注意到225例患者 (91%) 有内镜治疗指征。欢迎阅读本期第一篇精选论文。
据估计,不完全息肉切除占结肠镜检查后结直肠癌的很大一部分。 对于 4-9 毫米息肉,Pedersen 等人发现热圈套器和冷圈套器息肉切除术的不完全切除率相似,但未发现后者的非劣效性。 他们的国际多中心随机对照试验发现,锯齿状和增生组织学都是不完全切除的独立危险因素。欢迎阅读本期第二篇精选论文。
在本期的第三篇精选论文中,Moons 等人报告了内镜下肌间剥离术 (EID) 治疗深层黏膜下浸润性直肠癌的安全性和有效性。 在 67 名患者中,该技术涉及固有肌层的圆形和纵向部分之间的解剖,显示出 96% 的总体技术成功,81% 的 R0 切除(pT1sm2/3 为 90%)和 45% 的治愈性切除。 不良事件发生率为 12%,未见严重不良事件。
欢迎阅读本期三篇精选论文及其它全部论文。
Issue 10 · Volume 54 · October 2022
Original article
Nieuwenhuis Esther A et al.
The optimal management for patients with low grade dysplasia (LGD) in Barrett’s esophagus (BE) is unclear. According to the Dutch national guideline, all patients with LGD with histological confirmation of the diagnosis by an expert pathologist (i. e. “confirmed LGD”), are referred for a dedicated re-staging endoscopy at an expert center. Nieuwenhuis et al. aimed to assess the diagnostic value of re-staging endoscopy by an expert endoscopist for patients with confirmed LGD.
Original article
Pedersen Ina B et al.
Endoscopic screening with polypectomy reduces the incidence of colorectal cancer (CRC). Incomplete polyp removal may attenuate the effect of screening. This randomized trial compared cold snare polypectomy (CSP) with hot snare polypectomy (HSP) in terms of complete polyp resection.
Innovations and brief communications
Moons Leon MG et al.
The risk of lymph node metastasis associated with deep submucosal invasion should be balanced against the mortality and morbidity of total mesorectal excision (TME). Dissection through the submucosa hinders radical deep resection, and full-thickness resection may influence the outcome of completion TME. Endoscopic intermuscular dissection (EID) in between the circular and longitudinal part of the muscularis propria could potentially provide an R0 resection while leaving the rectal wall intact.