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本刊为国际性论文全文期刊，致力于推动合成化学科学的发展。它涵盖了所有涉及合成有机化学领域，包括催化、有机金属、医药、生物学和光化学，也包括其他相关学科。SYNTHESIS上的内容翔实地记载了实验流程，完整地描述了所有重要新产品，提供了可靠的研究成果和科学原始数据。